Effects of acute exercise on angiotensin I-converting enzyme (ACE) activity in horses

De Mello Costa, M. F. and Anderson, G. A. and Davies, H. M. and Slocombe, Ron (2011) Effects of acute exercise on angiotensin I-converting enzyme (ACE) activity in horses. Equine Veterinary Journal . ISSN 2042-3306

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Official URL: http://dx.doi.org/10.1111/j.2042-3306.2011.00461.x

Abstract or Summary

Angiotensin I-converting enzyme (ACE) level measurement in blood samples is an important tool in human medicine for the detection, treatment and control of diseases such as sarcoidosis and hypertension. Recently ACE has been advocated as being correlated to athletic aptitude in human athletes and a genetic polymorphism has been shown to be responsible for the enzymatic levels in the circulation. The objective of this research was to evaluate the effects of acute exercise in horses in order to increase the understanding of a possible correlation between ACE levels in plasma and performance in equine athletes. A standardised exercise test (SET) to fatigue was conducted on 8 horses and repeated venous blood collections carried out for ACE activity measurements before, during and after the SET. Our results show an increase in ACE activity up to fatigue and a return to baseline values at 30 min post exercise.

Item Type:Journal article
Keywords that describe the item:horse, exercise, angiotensin I-converting enzyme, ACE
Subjects:R Medicine > RC Internal medicine > RC1200 Sports Medicine
S Agriculture > SF600 Veterinary Medicine
Divisions:Schools > Centre for Science and Primary Industries
ID Code:1297
Deposited By:
Deposited On:28 Oct 2011 00:21
Last Modified:20 Dec 2018 00:23

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